Chemical Biology News

  • Review of antibacterial DNA supercoiling inhibitors

    The Royal Society of Chemistry's Designing Multi-Target Drugs provides a valuable resource for those interested in creating novel therapies for complex diseases. The chapter on anti-bacterial DNA supercoiling inhibitors "Ethyl Urea Inhibitors of the Bacterial Type II Topoisomerases DNA Gyrase (GyrB) and Topoisomerase IV (ParE)" by Stephen P. East, Lloyd G. Czaplewski and David J. Haydon will be particularly useful for those involved in or starting out in antibacterial drug discovery

    http://pubs.rsc.org/en/content/chapter/bk9781849733625-00335/978-1-84973-491-2

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