Antibacterial R&D

Creating new antibacterial medicines

Lloyd Czaplewski is an International Opinion Leader & successful Scientist Entrepreneur in the antibacterial R&D sector.

"Over 15-years experience in antibacterials has taught me what works & what does not. That is invaluable expertise that clients can benefit from"

Key successes:

Target validation - over 300 potential targets analysed in detail
Screening - over 150,000 compounds screened against multiple bacterial pathogens & targets

Created class-leading antibacterial DNA supercoiling GyrB/ParE ATPase inhibitors with competitive preclinical efficacy and pharmacology - ready for candidate nomination with a strong unrelated back-up series.

Created the first efficacious inhibitors of bacterial cell division that target the GTPase FtsZ

Devised portfolio growth strategies to address Gram-negatives targeting multi-drug resistant strains eg NDM-1, using innovative chemistry

Commercial success - building & selling an antibacterial business

You are viewing the text version of this site.

To view the full version please install the Adobe Flash Player and ensure your web browser has JavaScript enabled.

Need help? check the requirements page.

Get Flash Player